This is a text book example of a battle for Attrition. Logan can't kill Kharn as he would simply vanish to the warp only to return later. I also don't believe Gorechild (Kharns Axe) would do anything against comic-Adamantium.

Overall Kharn absolutely curb stomps Logan in QCQ, Both would never need to stop fighting due to their individual powers. If Logan can get in close and use those claws, then he can surely leave a mark.

Yes. Also wolverine’s healing factor can be slowed down if he goes through too much damage in a small amount of time. He can be drowned, and he can be killed if his head is (somehow) decapitated or his brain destroyed. If i remember correctly (correct me if im wrong), as a former Space Marine, Khârn has superman level strength essentially and can use that in his arsenal to possibly overload Wolverines healing factor and slow him down where he can easily get to his brain without much of a fight. On the other hand, the fight could be very drawn out, possibly even for years.

@TheMightyIronCaptainHulk

No one besides someone like the Emperor would posses Superman-levels of strength. Angron, one of the physically strongest Primarchs behind Vulkan, was almost killed just from lifting the leg of a warhound titan which probably only weighs a few hundred to a few thousand tons.

And secondly it can really depend on the version of Logan we are talking about. Some sources say just lopping off his head is enough, while others have him coming back form just a drop of blood.