Due to artificial nature powers may be less potent or nigh powerful when compared to regular God related powers.
Last Trinity (Trinity Seven); via absorbing the Magic King Element
Doomsday (DC Comics)
Reincarnation of Rao (DC Comics)
Super-Adaptoid (Marvel Comics)
Ultron (Marvel Comics); in certain incarnations
Lucy Miller (Lucy)
Will Caster (Transcendence)
AMAZO (DC Animated Universe)
Rex Salazar (Generator Rex); via Meta-Nanites
Elina (Breath of Fire IV)
Ragnarok (Valkyrie Crusade)
The Reincarnation of Rao (DC Comics) was an unstoppable creation of a possessed Kryptonian named Jax-Ur which absorbed any energy sent against it and used the energy to grow and increase its physical power.
Krishna (Supergod) is a man-made god from India designed to modify the country's environment at will, upgrading the infrastructure, and improving the entire country
After her body is exposed to high amounts of CPH4, Lucy Miller (Lucy) slowly evolves until she ascends into a higher plane, becoming one with the universe.
After transferring his mind into a computer, Will Caster (Transcendence) has achieved a form of godhood through artificial intelligence.
Ragnarok (Valkyrie Crusade) is a man made WMD machine deity, created to defy the gods.