The user can combine their bio-energy with physical combat abilities, tapping living energies to use for attack, defense and,/or augmenting physical prowess for battle.
- Prypiatosian-Bs (Ben 10)
- Shoto Todoroki (Boku no Hero Academia)
- Derek Powers/Blight (DC Animated Universe/Batman Beyond)
- Black Lightning (DC Comics)
- Derek James/Sideways (DC Comics)
- Jesse Aaronson/Bedlam (Marvel Comics)
- Kiwi Black (Marvel Comics)
- Miles Morales/Spider-Man (Marvel Comics)
- Senyaka (Marvel Comics)
- Biotics Users (Mass Effect)
- Shinobi (Naruto)
- Mink Tribe (One Piece)
- Appetite Energy Users (Toriko)
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