Santana (JoJo's Bizarre Adventure Part II Battle Tendency)
Foo Fighters (JoJo's Bizarre Adventure Part 6: Stone Ocean)
Miss Fortune (League of Legends)
Samus Aran (Metroid)
Train Heartnet (Black Cat) firing a gigantically destructive bullet of ki from his Tao Gun....
...and firing an Orichalcum bullet out of Hades, which is capable of destroying any material on Earth.
Durham Glaster (Black Cat) using his Shot ability to channel his ki through a gun barrel to shoot virtually limitless amounts of ki bullets that he can vary in size and destructive potential.
Yammy Llargo (Bleach) using Bala to fire off bullets of spiritual energy from his fists.
Aisslinger Wernarr (Bleach) rapidly firing blasts of spiritual energy from each of his fingertips.
Grimmjow Jaegerjaquez (Bleach) launching his claws as projectiles.
Coyote Starrk (Bleach) firing spiritual energy in the form of Ceros...
...and using his Cero Metralleta to fire a barrage of spiritual energy.
Ggio (Bleach) can throw the "Fangs" of his mask to great speed against his opponent.
Robert Accutrone (Bleach) generates bullets of condensed spiritual particles that ignites into blue flames.
Nemu Kurotsuchi (Bleach) using Konpaku Sessaku to split off 6% of her soul to fire off the Gikon Jūrinjū, a devastating projectile.
A Level 4 Akuma (D.Gray-man) turning its arms into Gatling guns that fires deadly Dark Matter blood bullets.
BurningGreymon (Digimon Frontier) fires solar heat-wave energy bullets from his Rudori Tarpana.
Krillin (Dragon Ball Z) breaking apart a ki blast into multiple Scattering Bullets.
Frieza (Dragon Ball Z) firing his Death Beam.
Vegeta (Dragon Ball Z) using the Bang! technique.
Pikkon (Dragon Ball Z) shooting generic energy bullets out of his ki.
Master Hades (Fairy Tail) shooting bullets of magical energy.
Pearl (Heroes) can destroy objects by firing "invisible bullets" via the traditional handgun gesture.
Shukaku (Naruto) using Wind Release: Drilling Air Bullet to produce a gigantic compressed air bullet capable of leveling an entire forest, and can even rapid-fire.
Danzō Shimura (Naruto) blowing out Wind Release: Vacuum Sphere, bullets of air capable of piercing through flesh with ease.
Gengetsu Hōzuki/Second Mizukage (Naruto) using his clan's Water Gun Technique to fire a compressed water bullet that can pierce through a sand clone.
Kimimaro (Naruto) using Ten-Finger Drilling Bullets to fire off his fingertip bones as drilling bullets.
Madara Uchiha (Naruto) using Yasaka no Magatama to fire off very destructive bullets of chakra.
Sasuke Uchiha (Naruto) using Inferno Style: Yasaka Beads/Blaze Release: Yasaka no Magatama to fire off very destructive bullets of black fire.
As they truly live up to their design of being robotic guns that are embedded into the ground or walls, the Turrets (New Blood Interactive's DUSK) can shoot bullets at various intruders they are programmed to take down.
Mr. 5 (One Piece) firing Breeze Breath Bomb, explosive air bullets produced from his breath.
Portgas D. Ace (One Piece) firing off his Fire Gun, bullets of fire.
Franky (One Piece) shooting Beans Left, regular bullets, from his wrist.
Borsalino/Kizaru (One Piece) firing a light-based laser beam from his fingertips...
...and a barrage of destructive photon bullets with his Yasakani no Magatama.
Donquixote Doflamingo's Tamaito(One Piece) fires a bullet of string capable of piercing skin.
Trafalgar D. Water Law (One Piece) using Injection Shot to fire a spatial bullet at Doflamingo from a distance, bypassing physical defenses
Yusuke Urameshi (Yu Yu Hakusho) channeling his Spirit Energy into his index finger to project his trusty Spirit Gun.
Younger Toguro (Yu Yu Hakusho) using his Finger Flip Bullet attack, projecting bullets of air with but a flick of the thumb.
The Panther King (Inuyasha)
Hiro Shishigami (Inuyashiki) firing an invisible bullet of telekinetic energy.
Shinobu Sensui (Yu Yu Hakusho) switching to his Kazuya personality, who pulls out an Energy Gun.
Reisen Udongein Inaba (Touhou Project)
Franklin's (Hunter x Hunter) Nen bullets.
Danny Fenton (Danny Phantom) can project his Ghost Rays in a gun style move.