- "Yeah, that demon ray gun stuff doesn't work on me."
- ― Sam Winchester to Samhain (Supernatural S4E7: It's the Great Pumpkin, Sam Winchester)
The user is immune to all or certain demonic powers and effects, making them able to withstand demonic power and go toe-to-toe with demons.
- Power Immunity to Demonic Powers.
- Still vulnerable to divine powers.
- More powerful demons (such as a transcendent demon) may be harder to be immune to.
- Immunity Bypassing users can nullify the immunity.
- Sam Winchester (Supernatural); initially limited to demonic white light, but immunity grew the more he drank demon blood, becoming immune to Alastair's Telekinesis.
- Dean Winchester (Supernatural); via the Mark of Cain, immune to Abaddon's powers.
- Kaldor Draigo (Warhammer 40,000) has been fighting daemons for hundreds of years while trapped in the daemonically-infested Warp and hasn't shown any signs of slowing.
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