Obtain abilities by ingesting specialized drugs. Though not a power in itself, it does grant powers to the user. Variation of Chemical-Based Powers and Equipment Usage.

Also Called

  • Drug Augmentation
  • Drug Empowerment
  • Drug Enhancement


The user can obtain superpowers by taking special drugs. However, most of the time the powers are either temporary or single use effect, and the user must continue to take the drugs to maintain their strength.




  • May become overdependent and/or addicted.
  • User may be powerless without the drugs.
  • May cause drowsiness.
  • User may suffer from an overdose or withdrawal.
  • Many other potential side-effects.

Known Drugs

  • ZenMetsu-gan Pill (Bobobo-bo Bo-bobo)
  • NZT-48 (Limitless franchise)
  • Rumble Ball (One Piece)
  • Energy Steroids (One Piece)
  • Three Coloured Pills (Naruto/Naruto: Shippuden)
  • Mind Awakening Pill (Naruto/Naruto: Shippuden)
  • Military Rations Pill (Naruto/Naruto: Shippuden)
  • Blood Increasing Pill (Naruto/Naruto: Shippuden)
  • Venom (DC Comics)
  • Titan (Batman: Arkham Asylum)
  • Plasmids (Bioshock)
  • Supersoldier Serum - Captain America (Marvel Comics)
  • Extremis Serum - Iron Man (Marvel Comics)
  • Infinity Formula (Marvel Comics)
  • Pym Particles (Marvel Comics)
  • Velocity 9 (DC Comics)
  • 5-U-83-R (Injustice: Gods Among Us)
  • Goblin Formula - Green Goblin (Marvel Comics)
  • D-Lite (Marvel Comics)
  • The Formula (Heroes)
  • Crank (Crank)
  • Regimen (Nikita)
  • ADAM (Bioshock)
  • EVE (Bioshock)
  • Catastrophe-A (Ghost Sweeper Mikami)
  • Draysha Gas (Champions Online)
  • Chems (The Bourne Legacy)
  • Celebre (GANGSTA.)
  • CPH4 (Lucy)
  • GH.325 (Agents of S.H.I.E.L.D.)
  • Centipede Serum (Agents of S.H.I.E.L.D.)
  • Drive (Xenogears)
  • Xemorene (Teenage Mutant Ninja Turtles)

Known Users

  • Immortal Ship Committee (Knights of Sidonia)
  • Titan Henchmen (Batman: Arkham Asylum)
  • Riley Finn (Buffy the Vampire Slayer)
  • Seiko Kimura(Danganronpa)
  • All Initiative operatives (Buffy the Vampire Slayer)
  • Bane (DC Comics)
  • Hourman (DC Comics)
  • NKVDemon (DC Comics)
  • Twilights (GANGSTA.)
  • Joker (Batman: Arkham Asylum)
  • New Fishman Pirates (One Piece)
  • Tony Tony Chopper (One Piece)
  • Snowflame (DC)
  • Akimichi Clan (Naruto/Naruto: Shippuden)
  • Kabuto Yakushi (Naruto/Naruto: Shippuden)
  • Orochimaru (Naruto/Naruto: Shippuden)
  • Captain America (Marvel); via Super Soldier Serum
  • Sentry (Marvel); via Super Soldier Serum but 1000X more powerful
  • Eddie Morra (Limitless)
  • Brian Finch (Limitless series)
  • Mayuri Kurotsuchi (Bleach)
  • Dr. Mario (Super Mario)
  • Splicers (Bioshock)
  • Misfits Gang (MisFits); they had they're powers reversed when they took ecstasy
  • Everyone (DWP)
  • Scott (Heroes)
  • Issac Mendez (Heroes)
  • Mohinder Suresh (Heroes)
  • Ando Masahasi (Heroes)
  • Nathan Petrelli (Heroes)
  • Tracy Strauss (Heroes)
  • Niki Sanders (Heroes)
  • Barbara (Heroes)
  • All Humans (Heroes); Alternate future
  • Johnny Quick (DC); Earth-3
  • The Dark Sage (Ninjustsu series) gave Human Rashi a special pill which unlock power but had a side effect
  • Patriot (Marvel)
  • Popeye (Popeye comic strip)
  • Mr. Hyde (Marvel)
  • Elongated Man (DC Comics)
  • Guardians (Nikita)
    • Owen Elliot/Sam Matthews (Nikita)
    • Patrick Miller (Nikita)
    • Jeff Shore (Nikita)
    • Dana Winters (Nikita)
    • Brandon (Nikita)
    • Tim (Nikita)
  • Motoki Yaze (Strike the Blood)
  • Tadao Yokoshima (Ghost Sweeper Mikami)
  • Jason Brody (Far Cry 3)
  • Lucy (Lucy)
  • Treadstone Assassins (The Bourne Identity)
  • Members of Operation Outcome (The Bourne Legacy)
    • Aaron Cross (The Bourne Legacy)
    • Number Three (The Bourne Legacy)
    • LARX-03 (The Bourne Legacy)
  • NKVDemon (DC)
  • Mike Peterson/Deathlok (Agents of S.H.I.E.L.D.)
  • Elhaym "Elly" Van Houten (Xenogears)
  • Basil (Dragon Ball Super)


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