Mine (Akame Ga Kill!) wielding the Roman Artillery: Pumpkin that fires spiritual energy bullets.
Coyote Starrk (Bleach) can fire powerful Cero from his dual pistols with deadly accuracy and potency.
Robert Accutrone (Bleach) fires bullets of condensed spiritual particles that ignites into blue flames with great skill.
Lille Barro (Bleach) the X-Axis is an expert marksman with a Reishi rifle.
Train (Black Cat) is a master marksman in accuracy and firing speed, especially with his Hades.
Toki (Code:Breaker) wields dual guns that are charged with magnetism to increase the force, and he can shoot with deadly accuracy.
Homer Simpson (The Simpsons) was so skilled with his gun that he was able to turn on the TV by shooting it at the right places.
Laguna Loire (Final Fantasy VIII) is skilled with guns.
Azureus (Azureus Rising) is skilled with guns.
Dante (Devil May Cry) is a master of the Gunslinger Style
which allows him to maximize the versaility and accuracy of Firearms to slay hordes of powerful demons.
Beelzemon (Digimon) is highly skilled in dual wielding his signature shotguns, the Berenjena.
BelleStarmon (Digimon) is highly skilled in dual wielding her signature revolvers, the Rizoma de Loto.
Shadow the Hedgehog (Sonic the Hedgehog), shows great skills in handling various firearms.
Julie-Su (Archie's Sonic the Hedgehog)
Zero (Kurohime) wielding his four guns at such speed and accuracy it appears he uses all four simultaneously.
Vash the Stampede (Trigun) is skilled at wielding various firearms, even dual wielding.
Revy (Black Lagoon) is so skilled using her dual modified Beretta M92 pistols that she goes by the moniker "Two Hands".
Jigen Daisuke (Lupin III) is an expert marksman. He can perform a 0.3-second quick-draw and has an accuracy that borders on superhuman; he can shoot skeet with a handgun, explode a missile before it hits by targeting the warhead, and deflect another bullet by shooting it in mid-flight.
Carmelita Fox (Sly Cooper) is incredibly adept at using her Shock Pistol.
Muggshot (Sly Cooper) wields numerous machine guns.
Toothpick (Sly Cooper) is an excellent shot, skilled with a variety of firearms that makes him a loose cannon
Whenever Aile (Mega Man ZX series) Double Megamerges to create Biometal Model ZX she acquires the shooting capabilities of X and the swordsmanship of Zero.
Officer Matthew "Matt" Cordell (Maniac Cop): "You have the right to remain silent...forever."
Panty (Panty and Stocking with Garterbelt) is able to form her panties into her spiritual gun, Backlace.
Much like her counterpart, Scanty (Panty and Stocking with Garterbelt) wields twin, golden revolvers the more powerful gun type than a common handgun.
Desperado (Valkyrie Crusade)
Isabel (Valkyrie Crusade)
Sharpshooter (Valkyrie Crusade)
...can use Shooters, like the Splattershot...
...Chargers, like the Splat Charger...
...and Splatlings, like the Heavy Splatling, all of which resemble guns, with proficiency.
...can use the Hero Shot...
...and the Hero Charger, both of which resemble guns, with proficiency.
Octolings (Splatoon) can use one weapon resembling a gun...
...the Octoshot, with proficiency.
April O'Neil (Teenage Mutant Ninja Turtles 2012 TV series)
The Fire Tank Pirates (One Piece) are highly skilled in wielding firearms such as revolvers and rifles
The Man With No Name (Dollars Trilogy) is truly a classic example of a skilled gunfighter.
Agent Whiskey (Kingsman) shows his remarkable gunmanship against a group of armed men.
Gill Bastar (WANTED!) was an extremely skilled gunman...
...outgunning and killing various bounty hunters with ease.
As an Eternal, Tien/Esser (Granblue Fantasy) is one of the most powerful and skilled gunfighters throughout the skies.
Nagumo Hajime (From Common Job to Strongest in the World) has outstanding marksmanship in dual wielding his technomagical revolvers Donner and Schlag.
A gifted sharpshooter, Guido Mista's (JoJo's Bizarre Adventure Part 5 Golden Wind/Vento Aureo) uncanny precision with a revolver, supported by his ability to keep his cool even in the middle of a gunfight, makes him a particularly deadly individual and assassin.
Lance (Voltron Legendary Defender)
Like his uncle, Nero (Devil May Cry) has incredible talent as a gunslinger...
...shooting down multiple demons with superhuman accuracy using his revolver Blue Rose
Satou Pendragon (Death March kara Hajimaru Isekai Kyousoukyoku) is a master gunslinger
accurately shoot down monsters from great distances.
Supersonic Van Augur (One Piece) is one of the world's greatest gunslingers. His marksmanship with his rifle Senriku is supreme, able to snipe the smallest targets over the greatest distances
Corporal Giroro (Sgt Keroro) has proven his supreme precision as the best gunman of the Keron Army.
Kurumi Tokisaki (Date A Live) is a supreme gunslinger, firing her dual musket and flintlock with supernatural accuracy.
Deadshot (DC Comic) is the world's greatest marksman, any firearms and artillery is extremely deadly in his hands.
As Captain of the Fire Tank Pirates, Capone Bege (One Piece) is one of the world's greatest marksmen, accurately rapid-firing bullets that can outpace even Katakuri's precognition...
.. sniping with perfect precision from tremendous distances using an ordinary flintlock.
Hush (DC Comics) has incredible skill in dual wielding M1911 .45 caliber pistols, able to match Batman's marksmanship with the Batarangs.
Trish (Devil May Cry Series) wielded twin demonic pistols Luce Bianca & Ombra Nera wth great skill.
Lady (Devil May Cry Series) is an exceptional all-around master markswoman with a variety of firearms and artillery.
Winter Soldier Bucky Barnes (Marvel Comics) is a master marksman with all types of military firearms and artillery.