Flame Princess (Adventure Time) launch a barrage of fireballs.
Ozai (Avatar: The Last Airbender) creates a firebomb.
Ultimate Kevin (Ben 10: Ultimate Alien) projecting flames.
Kyoko Kirisaki (Black Cat) using her Heat ability to spit out an explosive fireball.
Love Aikawa (Bleach) using Hifuki no Koduchi.
Momo Hinamori (Bleach) tosses a fireball to stop a Cero.
Dark Willow (Buffy the Vampire Slayer) produces a fireball.
Wesley Wyndam-Pryce (Buffy the Vampire Slayer/Angel) creating a fireball in his palm.
A member of The Triad (Charmed) creates a fireball.
Ciril (Charmed) generating a fireball.
Danny Phantom (Danny Phantom) creates two ectoplasmic fire balls.
Vegeta (Dragon Ball Z) can convert his ki into fire and project in the form of his Shine Shot.
Cole (Infamous) throwing giant fireballs with his pyrokinesis.
Natsuru (Kampfer) using Zauber magic.
Using his Nature ÄRM called Antares allows Halloween (Marchen Awakens Romance) to generate great balls of fire and hurl them at the enemy.
Leno (Marchen Awakens Romance) activates his Nature ÄRM, Flame Ball.
Guardian ÄRM, Phoenix (Marchen Awakens Romance) can shoot powerful balls of fire from its mouth creating a fiery explosion.
Mario (Mario series) is well known for projecting fireballs whenever he possesses the Fire Flower.
Obito Uchiha (Naruto) using Fire Release: Great Fireball Technique to breath a giant roaring ball of flames, capable of burning through an earthen wall.
Itachi Uchiha (Naruto) using the Fire Release: Great Fireball Technique, creating a roaring ball of flames.
Sasuke Uchiha (Naruto) using the Fire Release: Great Dragon Fire Technique, creating gigantic fireballs in the shape of dragon heads capable of changing the weather in the clouds...
... and Inferno Style: Yasaka Beads/Blaze Release: Yasaka no Magatama to fire off very destructive black fireballs.
Jiraiya (Naruto) using Fire Release: Flame Bullet to launch an oil-empowered fireball.
Portage D. Ace (One Piece) using his Hotarubi/Firefly Light to create greenish yellow fireballs...
...and his ultimate technique, Dai Enkai: Entei, a gigantic fireball.
Randy Cunningham (Randy Cunningham: 9th Grade Ninja) about to unleash the Tengu fireball.
Rei Hino/Sailor Mars (Sailor Moon) using Burning Mandala.
El Jefe (Sly Cooper: Thieves in Time) launching fireballs from his swords.
Blaze the Cat (Sonic the Hedgehog)
Zavok (Sonic the Hedgehog)
Robin (Super Smash Bros. Wii U) using Arcfire to cast a fireball.
Kavaxas (Teenage Mutant Ninja Turtles 2012) projecting balls of green flame.
Bravenwolf Tenkai Firestorm (Tenkai Knights) forming a giant fireball to attack.
Red-Eyes Black Dragon (Yu-Gi-Oh!) breathing out the Black Fire Bullet, an explosive fireball.
Katsuya Jonouchi (Yu-Gi-Oh!) using the illegal magic card, Fireball, to drop a fireball onto Yugi's life points.
Randō (Yu Yu Hakusho) using "Destructive Fire-Emitting Palm-Fist" to throw fireballs.
Zeru (Yu Yu Hakusho) launching a fireball via a punching thrust.
Ultimate Green Goblin (Marvel Comics)
Crazy Jane/Sun Daddy (Doom Patrol/DC Comics)
Zuko (Avatar: The Last Airbender)