Rokk Krinn/Cosmic Boy (DC Comics) is a charismatic and effective leader, as seen during his successful tenure as the Legion's first leader.
Emerald Empress (DC Comics)
Emerald Empress (Legion of Superheroes/DC Comics)
Granny Goodness (DC Comics)
Commander Cold (DC Comics)
The Batman Who Laughs (DC Comics)
Captain America (Marvel Comics)
Doctor Octopus (Marvel Comics)
Baron Zemo (Marvel Comics)
Houndeyes (Hλlf-Life series) strenght depends on the presence of leader.
A Red Sentai/Rangers (Super Sentai/Power Rangers) is always a hero with a burning sense of justice and usually the leader and the driving force of their respective teams.
Optimus Prime (Transformers)
Monkey D. Luffy (One Piece)
Ou Ki, the Monsterous Bird of Qin (Kingdom)
Shin of the Hi Shin Unit (Kingdom)
Kyou Kai, Second Lieutenant of the Hi Shin Unit (Kingdom)
Kan Mei, the Giant of Chu (Kingdom)
Shou Hei Kun, the Chief of Qin's Military Affairs (Kingdom)
Suu Gen, Infantry commander of the Hi Shin Unit (Kingdom)
Leonardo (Teenage Mutant Ninja Turtles), the leader of the four Ninja Turtles.
Raphael (Rise of the Teenage Mutant Ninja Turtles) is the leader of the teenage mutant ninja turtles.
Dark Leo (Teenage Mutant Ninja Turtles) is the leader of the dark turtles.
Alpha Werewolves (Teen Wolf) are the leaders of the packs and get stronger with every beta that joins them.
Scott (Teen Wolf) was able to rise to the Alpha through sheer force of will due to his compassion and great leadership skills, rather than having to steal the power through the act of killing an alpha.
Cobra Commander (G.I. Joe)
Major Chip Hazard (Small Soldiers)
Judge Death (Judge Dredd)
Genghis Rex (Dinosaucers)
Cy-Kill (Challenge of the GoBots)
Saw Boss (Jayce and the Wheeled Warriors).
White Shadow (Minoriteam)
Gideon Gordon Graves (Scott Pilgrim vs. the World)
Lord Recluse (City of Heroes/City of Villains)
Skeletor (Masters of the Universe)
Hordak (Masters of the Universe)
Psycho Red Ranger (Power Rangers)
Scorpix (Big Bad Beetleborgs)
Bombshell (Puppet Master)
Voltar (League of Super Evil)
S.P.H.I.N.X. Comamander (The Venture Bros.) is the leader of S.P.H.I.N.X.
Wes Warhammer (The Venture Bros.) is the leader of the doom factory.
Captain Ginyu (Dragon Ball Z)
Slappy the Dummy (Goosebumps)
Comrade Red (Dexter's Labraoratory)
Lord Dragaunus (Mighty Ducks)
Mr. Physically Fitastic (Codename: Kids Next Door)
Diamond Ryugu (Dinozaurs)
Triceratron (The Grim Advenutres of Billy & Mandy)
Iron Klaw (G.I. joe Extreme)
Golden Queen (Skylanders)
Johnny Worthington III (Monster University)
Laughing Man (Batman/Teenage Mutant Ninja Turtles III)
Brandon "Big Boss" Babel (COPS: the Animated Series) is the leader and mastermind of C.R.O.O.K.S. organization.
Stretch (Stretch Armstrong and the Flex Fighters) is the leader of the flex fighters.
All For One (My Hero Academia)