Sonic the Hedgehog with Metal Sonic (Sonic the Hedgehog: The Movie)
Peni Parker (Marvel Comics)
As Ally's guide dog, Barney (Misfits) communicates with her to tell her what is going on in her surroundings or to warn her of any danger.
Jodie Holmes (Beyond: Two Souls) has a natural mental link with a spiritually attached entity known as "Aiden".
Sensates (Sense8) are a race of humans who have a telepathic link with each other, which they can use to their advantage.
The Protoss (Starcraft) can commune with each other telepathically through the "Khala".
Dragons and their riders (Inheritance Cycle) develop a mental link the moment they touch each other.
Peni Parker (Marvel Comics) possesses a mental link with the radioactive spider that pilots the SP//dr Suit, both forming one half of the suit's CPU.
As Hyper Metal Sonic (Sonic the Hedgehog: The Movie) was programmed with Sonic's life data, the two share identical thought patterns, allowing them to predict the other's actions.
After a car accident that temporarily left him in a coma, Ethan Mars (Heavy Rain) mysteriously developed a mental link with a serial killer known as the Origami Killer, caused by the killer being present when the accident took place.
After being possessed by the Oracle, Lucas Kane (Fahrenheit/Indigo Prophecy) developed a mental link to him, which the latter was partially aware of.