The user can endure physical stresses beyond the capabilities of the greatest humans enabling them to do things such as operating on a "low power setting" (being able to operate efficiently for extended amounts of time), holding their breath for large periods, remain calm through stressful or painful situations, tolerate extreme hunger, unbearable thirst, and strong urges to sleep.
Practitioners of the Hercules Method (The Strange Talent of Luther Strode)
Violator/Clown (Image Comics)
Max Borne/Spider-Man 2211 (Marvel Comics)
Omni-Man (Image Comics)
Kobe Shakur (Ripley's Bureau of Investigation)
Patrick Donovan (The Young Guardians); via heat absorption
Black Dynamite (Black Dynamite)
Luther Hargreeves (The Umbrella Academy)
All Demigods (Asura's Wrath)
Asura (Asura's Wrath)
Yasha (Asura's Wrath)
Golems (Crypt of the NecroDancer)
Protagonist characters (The Elder Scrolls series)
Protagonist characters (Fallout); via Endurance skill & various perks
Lightning (Final Fantasy XIII)
Kratos (God of War series)
Antlion Guards (Hλlf-Life 2 series)
Antlion Guardian (Hλlf-Life 2: Episode Two)
Pokémon that can learn "Endure" (Pokémon)
Centroids (Quake: Scourge of Armagon)
Sonic the Hedgehog (Sonic the Hedgehog)
Storm the Albatross (Sonic the Hedgehog)
Zavok (Sonic the Hedgehog)
Fleshes (S.T.A.L.K.E.R. series)
Blind Dogs (S.T.A.L.K.E.R. series)
Boars (S.T.A.L.K.E.R. series)
Pseudodogs (S.T.A.L.K.E.R. series)
Psy Dogs (S.T.A.L.K.E.R. series)
Clawgrip (Super Mario Bros. series)
Geralt of Rivia (Witcher)
Despite his old age, Yamamoto (Bleach) is capable of fighting for long periods, even when outnumbered, with no visible signs of exhaustion.
During his fight with Byakuya, Renji (Bleach) is hit directly by every blade from Senbonzakura Kageyoshi, and when he continues to fight he is pierced by five more blades.
Komamura (Bleach) is capable of taking considerable amounts of damage and still able to fight, despite the severity of his injuries.
When in his Shinigami/Soul Reaper form, Ichigo's (Bleach) endurance is strengthened to the point where he can continue fighting effectively after receiving many injuries.
Byakuya (Bleach) is a very resilient fighter.
Shūkurō Tsukishima (Bleach) Was able to survive a fatal flow from Byakuya's Senbonzakura and continued fighting until he finally succumbed to his injury.
Vegeta (Dragon Ball series)
Kozuki Oden (One Piece) showing his immense endurance by holding up 9 grown men for an hour, while being boiled in oil.
Monkey D. Luffy (One Piece)
Rob Lucci (One Piece)
Naruto Uzumaki (Naruto) has a strong will of endurance.
Gemma (Ninja Scroll) can endure all injuries and fight back, due to his mastery over his own body.
Capable of fighting on despite excessive blood loss, Ri Shin's (Kingdom) immense endurance allows him...
...to fight for four days straight with little to no sleep...
Along with his impressive stamina, Kou Yoku of the Thunder (Kingdom) can endure the rapid attacks and strikes of the Tou Army officers as he fights on.
Since the days of being horrendously abused by the citizens of Kantan and his mother, Ei Sei (Kingdom) can endure an excessive amount of pain and blood loss after surviving an almost fatal sword slash across his neck.