Sarah Ravencroft's spell book (Scooby-Doo and the Witch's Ghost)
Gem of Cyttorak (X-Men: Evolution)
Awakening (Saga Frontier)
Heather Tobey (The 4400) used this ability to bring out the artistic potential in her students, as well as to improve Richard Tyler's telekinetic powers.
When worn, Power Surging: Balzac (Akame ga Kill) can tap into the wearer's body and mind and unlock its full potential, giving the wearer super speed, super strength, lightning-quick agility and unparalleled intelligence.
When in total darkness, such as the vacuum of space, Zs'Skayr (Ben 10) is able to access his full potential.
The Berserker Armor (Berserk) unlocks the wearer's full combat potential by disabling the body's subconscious limiters.
The Hogyoku (Bleach) unlocked the hidden potential in Orihime and Sado, answering their need to no longer be burdens.
Ichigo Kurosaki (Bleach) has gained the true Tensa Zangetsu, realizing his full potential.
Using the power of the Scythe, Willow Rosenberg (Buffy the Vampire Slayer) unlocks the potential of all Potential Slayers worldwide, turning them into full-fledged Slayers.
After being resurrected in his twelve-year-old body, Rupert Giles (Buffy the Vampire Slayer) was able to reawaken the great magical potential that he had repressed in his previous life.
Dendritic Cell (Cells at Work) can activate the potential of immune cells, boosting their power and turning them into Effector Cells for a short amount of time.
Spekkio (Chrono Trigger) was able to unlock the magical potential of everyone in Crono's party.
The Force Edge (Devil May Cry series) appears to be a simple blade at first...
...but when in contact with the Perfect Amulet...
...it becomes the Sparda, a Devil Arm with godlike power.
The Rebellion (Devil May Cry series) was able to awaken its full potential after coming into contact with the blood of its wielder, Dante...
...as well as awaken Dante's dormant potential and allow him to access his Devil Trigger.
Similary, The Yamato (Devil May Cry series), when restored by Nero's Devil Bringer...
...was able to help Nero (Devil May Cry 4) unlock his Devil Trigger, allowing him to summon a spectral demon avatar that wields Yamato and fires Summoned Swords.
Determined to prevent Dante and Vergil from killing each other, Nero (Devil May Cry series) was able to unlock his full demonic potential, allowing him to regenerate his severed right arm...
...and access his own innate Devil Trigger.
The X-Antibody (Digimon) not only makes a Digimon immune to the X-program, but also evolves them to stronger versions of their current forms by drawing out their latent potential.
By hugging a pure being, Cherubimon X (Digimon) can draw out their full potential.
Dark Spores (Digimon Adventure 02) draw out said hosts' academic and athletic potential, but also end up corrupting them as well.
In addition to placing others under his control, Babidi's (Dragon Ball series) magic also draws out their hidden power...
...something that Vegeta took advantage of...
...in order to gain the power to defeat Goku.
The Old Kai (Dragon Ball series) in the process of unlocking Gohan's full potential.
Gohan's (Dragon Ball) Potential Unleashed form is the result of having all of his dormant potential unlocked by the Old Kai.
The Ultra Divine Water (Dragon Ball) can unlock the potential and hidden powers of whoever drinks it, provided they survive...
....having drank it, Son Goku unlocked his hidden potential.
After being cornered by Goku in the final moments of the Tournament of Power, Jiren (Dragon Ball Super) became angered and awakened a deeper threshold of latent potential, achieving his Burning Ultimate Warrior state.
By the year 1000, the different incarnations of Shenron (Dragon Ball Online) are mostly used to unlock the full potential of humans, Namekians, and Majins, allowing them to transform.
The Guyver Units (Guyver) are engineered to adapt, conform, and enhance the physical characteristics of the host lifeform in order to maximize their full genetic potential.
By accepting his heritage, Hellboy (Hellboy/Dark Horse Comics) was able to unlock his full demonic potential.
The Keyblade of Heart (Kingdom Hearts) can unlock a person's heart and release their inner darkness...
...with Maleficent becoming a powerful dragon upon being stabbed with it.
By unlocking his different Drive Forms, Sora (Kingdom Hearts) is able to realize his full potential.
Ben Ravencroft (Scooby-Doo and the Witch's Ghost) used Sarah Ravencroft's spell book to unlock his latent potential as a warlock.
By forming bonds with Sonic and his friends and learning their skills and powers, Emerl (Sonic the Hedgehog) was able to unlock his nigh-unlimited fighting potential eventually becoming Ultimate Emerl.
The Warrior of Light (World of Final Fantasy) was once a mere soldier, but his potential as a Champion was awakened by the powers of Lann and Reynn.
By activating his chi, Omi (Xiaolin Showdown) is able to unlock his full potential.
The Super-Soldier Serum (Marvel Comics) brought out Steve Rogers' full potential...