Cape Canaveral Air Force Station (JoJo's Bizarre Adventure Part VI: Stone Ocean); Only after performing all other parts of the Heaven Ascension process.
The Devil's Palm (JoJo's Bizarre Adventure Part VII: Steel Ball Run)
The Wall Eyes (JoJo's Bizarre Adventure Part VIII: JoJolion)
Mammoth Mogul (Archie's Sonic the Hedgehog) bestowed Mighty with super-strength...
...and Mina with super-speed.
Compound V (The Boys) is a drug created by the Nazi scientist John Vogelbaum that grants superpowers to anyone who is injected with it, and is the source of every single superheroes' powers and The Boys themselves.
The wizard Shazam (DC Comics) passing his power to Billy Batson.
While under a blue sun, Superman (DC Comics) develops "Superman Vision" that enables him to grant Kryptonian powers to others…
…as demonstrated here on Jonathan Kent.
Each of the twelve talismans (Jackie Chan Adventures) grants the user a power stolen from the Noble Animals.
Rainbow-Colored Comet (Kim Possible)
With the power of the Butterfly/Moth Miraculous, Hawk Moth (Miraculous Ladybug) has the power to turn others into supervillains, bestowing on them an arsenal of unique superpowers.
Puppeteer (Miraculous Ladybug) is able to possess anyone who's doll she possesses. Should the doll be of a purified supervillain, they regain their villain identity along with their powers.
Ragtag (Static Shock) can give powers to others, but they are only temporary.
Him (Demashita! Powerpuff Girls Z) is able to create black dust, a mass of evil particles that are able to turn normal people or objects into supervillains, along with their own set of superpowers and persona.
Ananke (The Wicked + The Divine) bestows onto others their godly identities, as well as all of their divine abilities.
Woden (The Wicked + The Divine) is able to bestow godly abilities to regular humans.
Cassandra Igarashi/Urdr (The Wicked + The Divine) was able to bestow her friends powers similar to herself along with a shared hive-mind, collectively becoming the Norns.
General Bu (Master Raindrop) using the ranger mask.