Juggernaut (Marvel Comics) gains his near unstoppable strength from bonding with the powerful Crimson Gem of Cyttorak.
Nemesis (Marvel Comics) as the living physical embodiment of the Infinity Gems, possesses all their powers of Space, Time, Power, Soul, Reality, Mind and Ego.
Pip Crystals (My Life as a Teenage Robot) are among the most powerful and dangerous artifacts in the universe.
Crystal Heart (My Little Pony: Friendship is Magic)
Geodes (My Little Pony Equestria Girls)
Rock of Kissteria (Scooby-Doo and Kiss: Rock and Roll Mystery)
Aeon Crystal (Teenage Mutant Ninja Turtles 2012 TV series)
Tenko and her friends (Tenko and the Guardians of the Magic) in their super-powered forms granted by their respective Starfire Gems. From left to right: Bolt, Steel, Tenko and Hawk.
The Power Stones (ThunderCats 2011) are four mystical stones that grant special abilities once they're fused to a weapon, or a piece of armor. From left to right: Tech Stone, Soul Stone, War Stone/Eye of Thundera, and Spirit Stone.
The Chaos Emeralds (Sonic the Hedgehog) are a set of supernatural gems that allow the user to do varying things from powering machinery, controlling space-time, to gaining the ability of transformation.
The Master Emerald (Sonic the Hedgehog) has/grants the user the ability to nullify the powers of the Chaos Emeralds and keeping them in check.
Sol Emeralds (Sonic the Hedgehog)
Chaos Crystals (Sonic Boom)
The Eidoliths (FFXIII) are crystalline items which Lightning and her party use to summon forth their respective Eidolons into battle.
Crystals (Final Fantasy) are legendary elemental stones and objects that have power over natural phenomena, and function as a powerful source of magical energy. Many antagonists focus their efforts on seizing the crystals to gain power towards their goal.
The Power Stones (Power Stone series) are legendary stones of mysterious power that are said to make dreams come true. When three are collected, the collector is able to access a Power Change to become a more powerful version of himself/herself
The seven Power Stones (Power Stone anime) are each able to grant its bearer incredible power. When the seven stones are united, they can create the Light Stone and bring about an age of miracles and wonder.
Warpstone (Warhammer series), also known as wyrdstone, is solidified Chaos. As the raw stuff of Chaos it is the ultimate magical substance and greatly sought after by the followers of Chaos.
Jewel Girl (Valkyrie Crusade) has the ability to manipulate gems, and as well derive and use special powers of every gem.
The dragons (Combat of Giants) derive their powers from the gems they hoard, with a unique bonus effect if used by a dragon of that element.