Thanks to their massive brain that’s found within their entire body, Kingpins (Hλlf-Life) can use psychic attacks and defenses. The only drawback however, is that their psionic defense is limited to only protecting them from projectile weapons.
All Combine Advisors/Shu'ulathoi (Hλlf-Life 2 series) have a number of psionic abilities such as Telepathy, Telekinesis, etc.
Psycho Mantis (Metal Gear Solid)
The Sorrow (Metal Gear Solid 3: Snake Eater)
Silver the Hedgehog (Sonic the Hedgehog)
Krystal (Star Fox)
Kamek (Super Mario)
The Black Ops Psionic Amplifier/Psi Amp (System Shock 2) gives the wielder a great amount of psionic abilities.