Thanks to their massive brain that’s found within their entire body, Kingpins (Hλlf-Life) can use psychic attacks and defenses. The only drawback however, is that their psionic defense is limited to only protecting them from projectile weapons.
All Combine Advisors/Shu'ulathoi (Hλlf-Life 2 series) have a number of psionic abilities such as Telepathy, Telekinesis, etc.
Cole MacGrath (Infamous)
Athena Asamiya (The King of Fighters)
Raziel (Legacy of Kain)
Kain (Legacy of Kain)
Princess Zelda (The Legend of Zelda)
Ghirahim (The Legend of Zelda: Skyward Sword)
Psycho Mantis/Tretij Rebenok (Metal Gear Solid)
The Sorrow (Metal Gear Solid 3: Snake Eater)
Aya Brea (Parasite Eve)
Krystal (Star Fox)
Kamek (Super Mario)
The Black Ops Psionic Amplifier/Psi Amp (System Shock 2) gives the wielder a great amount of psionic abilities.