Twinrova (The Legend of Zelda: Oracle of Seasons and Oracle of Ages)
Users of Dark Magic (The Dragon Prince)
By sacrificing the House of Erebus, Deacon Frost (Blade) became the avatar of La Magra.
Genryūsai Shigekuni Yamamoto (Bleach) sacrificed his arm to activate "Hadō 96: Ittō Kasō".
The potion Voldemort (Harry Potter) used to regain his body required his servant to willingly sacrifice a piece of flesh as one of the three ingredients.
Lily Potter (Harry Potter) sacrificed her own life to grant Harry a powerful protection.
Twinrova (The Legend of Zelda: Oracle of Ages and Oracle of Seasons) sought to sacrifice Princess Zelda to resurrect Ganon, but due to Link's interference, they were forced to sacrifice themselves instead.
Belasco (Marvel Comics)
Nico Minoru (Marvel Comics)
Tzekel-Kan (The Road to El Dorado)
Unlike regular ÄRMs, creating the forbidden Ghost ÄRMs (Marchen Awakens Romance) requires great amounts of magical and physical energy, often leading to sacrificing entire lives.