User has extraordinary skills with the study and utilization of the field of science to produce mass inventions, conduct experimentation and perform accurate calculations. They have vast knowledge in a variety of branches of science as well (biology, chemistry, physics, mathematics, psychology, technology, geography, etc.) and are able to use their scientific expertise to create weapons, produce lifeforms or clones and experience various types of travel (time travel, space travel or extra-dimensional travel).
Various members of the Brainiac Family (DC Comics) are extremely skilled and proficient experts in various fields of science.
Michael Holt, Mister Terrific (DC Comics) is considered the third smartest man in the world, a brilliant inventor.
Superman (DC Comics)
Scarecrow (DC Comics)
Denzel Crocker (Fairly OddParents)
Stewie Griffin (Family Guy)
Jumba (Lilo & Stitch) considers himself as a "Evil Genius".
Norman Osborn/Green Goblin (Spider-Man)
Otto Octavius/Dr. Octopus (Marvel Comics)
Despite his appearance, The Sugar Man (Marvel Comics) is skilled Geneticist and creator of the Mutate Bonding Process.
Reed Richards (Marvel Comics)
Donatello (Teenage Mutant Ninja Turtles)
Baxter Stockman (Teenage Mutant Ninja Turtles)
Rick Sanchez (Rick and Morty)
Cyborg (DC Comics)
Agatha Heterodyne (Girl Genius)
Professor Utonium (The Powerpuff Girls)
Dr. Henry "Hank" Pym (Marvel Comics)
Dr. Nathaniel Essax/Mister Sinister (Marvel Comics) is a genius with expertise in various fields of science, mainly genetics with years of his research at his command, mutations and their powers, human and alien biology, cloning, all levels of physics, and engineering.
Egghead (Marvel Comics)
Peter Parker/Spider-Man (Marvel Comics)
Lisa Loud (The Loud House)
Johnathan Rook (Stretch Armstrong and the Flex Fighters)
Dexter (Dexter’s Laboratory)
Ferb alter their formula to produce positive effects
Ooboshi Ringo (Choujin Koukousei-tachi wa Isekai demo Yoyuu de Ikinuku you desu!) is the most brilliant scientific genius the world has ever known.
Dr. Gero (Dragon Ball Z)
Edward Elric (Fullmetal Alchemist)
Dr. Vegapunk (One Piece) is the leading scientist in the employment of the Marines. His work includes various scientific achievements that are said to be at least 500 years ahead of current technology.
Indigo (One Piece Film: Strong World) is a chemist and the sole-developer of the SIQ serum which caused fantastic mutations within various animals, plant life and humans.
Caesar Clown (One Piece) is a mad scientist and leading expert of chemical-based weapons of mass destruction.
Vinsmoke Judge (One Piece) is a brilliant master biologist with immense knowledge in genetics, cloning technology and genetic enhancement techniques.
Franky (One Piece) is a genius engineer/shipwright, through self studying of Dr. Vegapunk's military technology, performed various upgrades on his bionic body with a variety of scientific-based weaponry.
Dr. Genus (One Punch Man) is accomplished scientist in bio-molecular enhancement, modifying animal genetics, cloning himself, and creating a formula to restore his youth and live forever.
The Ghost Chess (Marchen Awakens Romance) is a unit in the Chess Pieces formed to invent and experiment on people with the forbidden Ghost ÄRMs.