"It does not stop at a mere single mutation... the form I've been promised is more beautiful than even that... They tell me I will float through the air and strike at the foes of our biomass with my mind... with our mind... my cup runneth over..."
― William Diego, hinting he will eventually become a Psi Reaver. (System Shock 2)

The power to undergo secondary mutations. Technique of Mutant Physiology.

Also Called

  • Further Mutation
  • Multiple Mutations


User who has already been mutated in some way develops a "secondary mutation," often gaining new powers or expansions on their existing ones. In some cases, the user's body mutates even further as well.

The secondary mutations can either be naturally or artificially induced.



  • Mutations may be uncontrollable.
  • Some mutations may cause changes in behavior and personality.

Known Users

  • Wayland Jonas/Killer Croc (Batman: Arkham/DC Comics)
  • Zombies (Hλlf-Life series)
  • Mohinder Suresh (Heroes)
  • Daxter (Jack and Daxter series)
  • Homo Superior/Mutants (Marvel Comics)
    • Henry McCoy/Beast
    • Warren Worthington III/Angel
    • Emma Frost
    • Remy LeBeau/Gambit
    • Josh Foley/Elixir
    • Quentin Quire/Kid Omega
  • Hybrids (System Shock 2)
  • Zombies (Resident Evil Series)
  • Peter Parker/Spider-Man (Spider-Man: The Animated Series); formerly
  • Morbius (Spider-Man: The Animated Series)
  • Ninja Turtles (Teenage Mutant Ninja Turtles 1987 TV series); temporary
  • Donatello (Teenage Mutant Ninja Turtles 2003 TV series); temporary
  • Leonardo/Maximus Kong (Teenage Mutant Ninja Turtles 2012 TV series)
  • Chris Bradford/Dogpound/Rahzar (Teenage Mutant Ninja Turtles 2012 TV series)


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