Superpower Wiki
"Heroes aren’t born, They’re made!"
― (The Boys)
"The super serum doesn’t turn us into monsters, it only brings out the truth of what we are inside, whether it’s perfect or not."
― (Anonymous)
"Ever since I was blown off from that roof. All I felt is pain. Pain of betrayal. Pain of having every bone in my body shattered. When I hit the water…I didn’t panic. I was patient. I let patience…Help me to find a way to transform that pain into something else…Strength."
― Ricardo Diaz (Arrowverse)

The ability to gain powers from certain serums. Sub-power of Serum Manipulation. Combination of Drug Usage and Powers Via Object. Variation of Chemical-Based Powers. Scientific equivalent of Potion-Based Powers.

Also Called

  • Powers via Serum
  • Serum-Based Enhancement
  • Serum-User Physiology
  • Super Serum Powers


The user can gain powers by being given a certain serum that augments one’s physical body. Some users can be turned into super soldiers after being given a serum. Some users can be turned into metahumans/mutants or mutates after being given a serum. If users are female and pregnant, as they’re being given a serum, their children may also gain powers once they’re born. If most users are male and have children with non-superpowered individuals, they may inherit their powers.

Some serums can be engineered by certain ingredients that may include chemicals/drugs or cells/blood from aliens, superhumans, etc.

Applications (General)

Applications (Details)



  • Users may experience unpredictable side effects from the serum:
  • Depending on if the serum has time limits, the effects of the serum, which grants the user powers, may not last forever.
    • Thus the user may have to constantly inject themselves with the serum daily.
  • Depending on the effects the serum has on physical age, infants/children or teenagers may have better adaptation to the effects of the serum than adults.

Known Users

  • Eldians (Attack on Titan)
  • Supers (The Boys)
    • Stormfront
    • The Seven
      • Homelander
      • Queen Maeve
      • Black Noir
      • Starlight
      • A-Train
      • The Deep
      • Translucent
      • The Lamplighter
      • Mister Marathon
      • Shockwave
      • Supersonic
    • Payback
      • Soldier Boy
      • Eagle the Archer
      • Crimson Countess
      • Tek Knight
      • Gunpowder
      • Swatto
      • Mindstorm
      • TNT Twins
    • The Boys
      • The Female/Kimiko Miyashiro
      • Billy Butcher (Temporarily)
      • Hughie Campbell (Temporarily)
    • Sage Grove Center
      • Cindy
      • Love Sausage
      • Tim
      • Phasing Patient
      • Tongue Patient
      • Wall Punching Patient
      • Zapped Lights Patient
      • Tiny Hero
      • Acid Vomit Patient
      • EMP Dude Patient
      • Glowing Eyes Patient
    • Airburst
    • Behemoth
    • Big Game
    • Blindspot
    • Doppelganger
    • Ezekiel
    • Gecko
    • Kenji Miyashiro
    • Laser Baby
    • Mesmer/The Mesmerizer
    • Malchemical
    • Naqib
    • Popclaw
    • Stacker
    • Victoria Neuman
    • Moonshadow
    • Silver Kincaid
    • Livewire
    • Blue Hawk
  • Supes (The Boys Presents: Diabolical)
  • Various Metahumans (DC Comics)
    • Slade Wislon/Deathstroke
  • Lois Lane (DC Comics/All-Star Superman)
  • Lex Luthor (DC Comics/All-Star Superman)
  • Various Characters (DC Comics/Arrowverse)
    • Ricardo Diaz (Arrow)
    • Slade Wilson (Arrow)
    • Various Metahumans (Black Lightning)
      • Green Light Babies
        • Maryam Luqman
        • Erica Moran
        • Issa Williams
      • Lynn Stewart; Temporarily
      • Original Vaccine Kids
        • Jefferson Pierce/Black Lightning
        • Looker
        • Wendy Hernandez
        • Baron/"T.C." Technocrat
        • Carson Williams
      • Tobias Whale
      • Tyson Sykes/Gravedigger ; Formerly
    • Users of Velocity-9 (The Flash)
      • Hunter Zolomon/Zoom
      • Eliza Harmon/Trajectory
      • August Heart/Godspeed
    • Nathaniel "Nate" Heywood/Steel (Legends of Tomorrow)
  • Various Mutates (Marvel Comics)
    • Super Soldiers (Marvel Comics/Marvel Cinematic Universe)
      • Steve Rogers/Captain America
      • Alexei Shostakov/Red Guardian
      • Winter Soldiers
        • Bucky Barnes/The Winter Soldier
      • Isaiah Bradley
      • Johann Schmidt/Red Skull
      • John Walker/Captain America/U.S. Agent
      • Flag Smashers
        • Karli Morgenthau/Flag-Smasher
      • Peggy Carter/Captain Carter
      • Robert Reynolds/Sentry
    • Norman Osborn/Green Goblin
  • Beast (Marvel Comics/X-Men Movies)
  • Luther Hargreeves/Number One/Spaceboy (The Umbrella Academy)

Known Serums

  • Titan Serum (Attack on Titan)
  • Compound V (The Boys)
  • V24 (The Boys)
  • Super Serum (DC Comics/All-Star Superman)
  • Mirakuru Serum (DC Comics/Arrowverse)
  • Original Vaccine (DC Comics/Arrowverse)
  • Velocity-9 (DC Comics/Arrowverse)
  • Green Light (DC Comics/Arrowverse/Black Lightning)
  • Meta Booster (DC Comics/Arrowverse/Black Lighting)
  • Anti-Aging Serum (DC Comics/Arrowverse/Black Lightning)
  • Harun-El/Rock of Yuda Kal/Black Kryptonite (DC Comics/Arrowverse/Supergirl)
  • OZ Formula/Goblin Serum (Marvel Comics)
  • Super Soldier Serum (Marvel Comics/Marvel Cinematic Universe)
    • Dr. Erskine's Early Prototype Serum
    • Dr. Erskine's Perfected Serum
    • Zola's Super Serum
    • U.S. Military Super Serum
    • Howard Stark's Super Serum
    • The Other US Military Super Serum Variant
    • Hulk Serum/Gamma Serum
    • The Abomination Formula
    • Nagel's Super Serum
  • Mutant Growth Hormone (Marvel Comics/X-Men Films)
  • Trilsettum Serum (No Ordinary Family)
  • Infinity Formula (Marvel Comics)