Turles (Dragon Ball Z: The Tree of Might) holding a Fruit of the Gods, which was spawned by the Tree of Might when it absorbed an entire planet's natural energy, granting its eater massive increase in power.
Locacaca Fruits (JoJo's Bizarre Adventure Part VIII: JoJolion)
Produced by Divine Tree, the Chakra Fruit (Naruto) grants the consumer incredible reserves of chakra.
A Rubber Human, Monkey D. Luffy (One Piece) became a "superhuman" or Paramecia class Devil Fruit user after accidentally eating the Gum-Gum Fruit/Gomu Gomu no Mi as a kid.
A Fire Human, Portgas D. Ace (One Piece) became an "elemental" or Logia class Devil Fruit user after eating the Flame-Flame Fruit/Mera Mera no Mi.
A Leopard Human, Rob Lucci (One Piece) became an "animalistic" or Zoan class Devil Fruit user after eating the Cat-Cat Fruit/Neko Neko no Mi: Model Leopard.
Adam and Eve (Biblical Mythology) once ate the Forbidden Fruits which granted the knowledge of good and evil, but with the price of being cursed by the concept of sin in disobeying God and are forever cursed with the knowledge of sin.